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Even in resting cells, up to 2% of oxygen uptake is converted into ROS ( GSH not only participates in protection against oxidative stress but also performs relevant functions in various cellular processes, such as cell proliferation, apoptosis and differentiation, and the inactivation of toxic electrophilic compounds (Valdovinos-Flores and Gonsebatt, 2013)

* Washout period refers to the time from the last administered dose to the time of the start of the In-Competition period (i.e

doi:10.1111/acel.12006

[oai_citation:1PubMed]( 2) Nitric-oxidemediated, largely endothelium-dependent vasorelaxation Aortic ring experiments showed vasodilation that was blunted by L-NAME and hemoglobin and attenuated without endotheliumconsistent with NO-mediated effects

[DOI] [PMC free article] [PubMed] [Google Scholar] 129.Brauer H.A., Libby T.E., Mitchell B.L., Li L., Chen C., Randolph T.W., Lampe P.D