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Amer Soc Clin Onc 3:195, 1984

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It has been suggested that cytoprotection may be due to bilirubin directly inhibiting NADPH oxidase activity, thereby reducing superoxide generation [180]

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Even the production is reduced by 10%, the ability for the body to detoxify is reduced by 10%

Inhibitory effect of melatonin on necroptosis via repressing the Ripk3-PGAM5-CypD-mPTP pathway attenuates cardiac microvascular ischemia-reperfusion injury