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Contributing factors include inadequate oral hygiene, smoking, nutrition, stress, and systemic conditions such as diabetes and heart disease

Researchers now are working on safer and less toxic drugs that potentially could enhance cognition

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J Exp Anal Behav 20 : 119129

The Toll of Tobacco in the U.S

For the first time, this has given us high-certainty evidence that e-cigarettes are even more effective at helping people to quit smoking than traditional nicotine replacement therapies, like patches or gums. In studies comparing nicotine e-cigarettes to nicotine replacement treatment, significant side effects were rare