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Health Policy 11 , 237249 (2013)

Polyphyllin I inhibits growth and invasion of cisplatin-resistant gastric cancer cells by partially inhibiting CIP2A/PP2A/Akt signaling axis

137141 Proteins are nonenzymatically modified by lipid-derived electrophiles that are generated by lipid peroxidation (LP) when cells are under oxidative stress (see Disruption of Redox Balance and Nrf2 Activation)

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Results can be influenced by factors like overall health, lifestyle, and consistency of treatments 2

Other research in mice, however, has shown that oxidative stress and inflammation brought on by aging lower NAD+ production (8). Therefore, it is likely that a number of mechanisms work together to cause individuals to lose NAD+ as they age