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[151] In 1934, George Whipple shared the 1934 Nobel Prize in Physiology or Medicine with William P

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25 Patients diagnosed with vitamin B 12 deficiency whose history and physical examination do not suggest an obvious dietary or malabsorptive etiology should be tested for pernicious anemia with anti-intrinsic factor antibodies (positive predictive value = 95%), particularly if other autoimmune disorders are present

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The combination therapy resulted in significant improvement in pain, fatigue, sleep, and depression compared to duloxetine and pregabalin alone

To many, these may be written off as everyday aches and pains, but usually they are signs