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Oral administration proved equally effective as injection in gastrointestinal models, a distinction that sets BPC-157 apart from peptides that degrade under digestive conditions

However, the peptide had minimal side effects in mice.

In age-related diseases and more particularly in IPF, mice treated with FOXO4-DRI display less senescent cells leading to a reduction of the progression of fibrosis 28

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Being investigated for its role in cellular activity and maintenance

The publication of high-quality mechanistic studies, coupled with small human trials showing functional endocrine and immune effects , has elevated the peptide from fringe curiosity to a serious candidate in the longevity toolkit