These results suggest that targeting FSP1 or inhibiting its phase separation initiates ferroptotic cell death is a potential anticancer paradigm
The interplay between mitochondrial dynamics and mitophagy
GO enrichment analysis indicated that the upregulated DEGs in the hypo group were mainly enriched in pathways related to oxidative stress, cell death, and aging, while the downregulated DEGs were enriched in cell adhesion and subsequent embryo development (Figure 4B)
Supervitamina is effective for treating anemia, and it is also an appetite stimulant
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Similarly, PCM nano-inducers enhance proteotoxic stress through cuproptosis, leading to the release of mitochondrial DNA that activates the cGAS-STING pathway, thereby initiating a robust immune response that significantly inhibits tumor progression and metastasis (Yu et al., 2024)