NLP was found to be mainly located in the cytoplasm, while the distribution of NESF was more diffuse and was also found in the nucleus
For example, senescent astrocytes show upregulated expression of IL-6, IL-8, IL-1, MMP3, MMP10, and TIMP2, while neuroprotective factors such as IL-10, NGF (nerve growth factor), and BDNF (brain-derived neurotrophic factor) are downregulated (Lye et al., 2019)
doi: 10.1007/s42000-018-0033-5 105 ChartoumpekisDVZirosPGHabeosIGSykiotisGP
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The ages of the male and female partners were 36 and 31 years, respectively