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Moreover, GMDZD is widely enriched in a series of signaling pathways, such as hypoxia inducible factor-1 (HIF-1), TNF, and toll-like receptors, which may also participate in the antidepressant effects of GMDZD [36]

Healthcare providers may recommend an initial treatment period of 4-6 weeks with 1-3 doses per week [21]

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10.1007/s11897-024-00643-3 86 DavidovM.KakaviatosN.FinnertyF

It can modify thiol groups, resulting in the production of S-nitrosothiols, as well as nitrate tyrosine residues (Prez de la Lastra et al., 2022)