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doi: 10.1167/iovs.03-0353

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POLRMT encodes for the mitochondrial RNA polymerase 26 that plays a critical role in transcription in pancreatic beta-cells and insulin secretion in the pancreas 69

Smoking and Pollution Exposure Cigarette smoke introduces a massive amount of free radicals into the lungs and bloodstream, and pollution from traffic and industrial areas does the same