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9 , eadi8291 (2023)

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Endometrial stem cells repair injured endometrium and induce angiogenesis via AKT and ERK pathways

1125 The antioxidative effects of ketone bodies on mitochondrial function occur primarily by regulating mitochondrial respiratory complexes, reducing ROS levels, and enhancing antioxidant capacity

Abstract Background: Although oxidative stress is known to contribute to cancer, and endogenous and exogenous antioxidants are thought to prevent tumorigenesis by suppressing oxidative stress-induced DNA damage, antioxidants have also been reported to show negative effects on tumor formation, necessitating characterization of the causal associations between antioxidants and cancer risk

Combination of FLT3 Inhibitor Quizartinib and MDM2 Inhibitor Milademetan Results in Greater Pre-Clinical Anti-Leukemic Activity in FLT3-ITD Mutant/P53 Wild-Type Acute Myeloid Leukemia Models