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Metabolic syndrome: definitions and controversies

5.2.2 Compound-specific toxicity thresholds and safety profiles 5.2.2.1 Curcumin: hepatotoxicity emergence and bioavailability concerns Recent evidence has highlighted emerging hepatotoxicity concerns associated with curcumin, particularly in the context of enhanced bioavailability formulations

This finding adds strength to the prevailing notion that glutamatergic excess plays a critical role in shaping the poor outcome trajectory in psychosis