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The results were robust to various sensitivity analyses, although the sparsity of observations limited the sensitivity analyses that were feasible (Fig

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As shown in Supplementary Table S1 online, the full range of available LD50 values in different animal species is taken into account as a risk function assuming a normal distribution for BMDL10 rather than that a single value is entered into the calculation (except methamphetamine and MDMA for which only one value was available in the literature)

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