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Ok, so these are interesting points but please add this into the mix for future answers: The NICE Guideline clearly states that there is insufficient research why some people need more frequent injections than others and that an 8- or 12- weekly schedule does not work for everyone and some may need more frequently

10.1155/2019/9084643 38 KovalcukaL.BirgeleE.BandereD.WilliamsD

Consequently, studies centered on single targets often fail to accurately reflect the overall therapeutic effects of drugs [236,237,238]

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