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Peptides like DSIP (Delta Sleep-Inducing Peptide) directly enhance sleep quality

Glutathione depletion enhances the formation of endogenous cyclic DNA adducts derived from t-4-hydroxy-2-nonenal in rat liver, Chemical Research in Toxicology

Similarly, ethanol-related increases in ROS generation are a prime factor in ethanol neurotoxicity

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Chaudhary, E., & Rahi, D

36 In some situations, the specific risk factor may have been mitigated and is no longer a concern (e.g., a high triglyceride level that is now within normal range, previous excess alcohol use in a patient who is currently sober, history of gallstones since resolved by cholecystectomy)