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[1] Because the cypionate ester markedly increases lipophilicity, the subcutaneous or intramuscular depot undergoes gradual enzymatic hydrolysis, releasing free estradiol that is chemically identical to endogenous estrogen and capable of binding to nuclear estrogen receptors in target tissues

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Contemporary Oncology 3:10-25, 1993

These findings might indicate why HGF/c-MET-positive lymphomas have a poorer prognosis [27]

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