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1 2 "Effect of monoamine reuptake inhibitor NS 2330 in advanced Parkinson's disease"

If freezer storage isn't available, refrigeration at 2-8C (36-46F) maintains stability for several months

In animal models, reducing light exposure has been shown to diminish photoreceptor degeneration

Budget-conscious protocol maximizing value Constraints: Limited financial resources requiring prioritization

Specifically, PER3 expression was significantly reduced and circadian rhythmicity disrupted in workers on multiple consecutive NS compared to those on a single NS or daytime shifts 209

In March 2011, the FDA placed the trial on clinical hold due to GMP compliance issues at the contract manufacturer not safety concerns with RGN-352 itself