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Clinically, a meta-analysis of 14 randomized controlled trials ( n = 1,154) found that probioticTCM combinations were superior to 5-ASA monotherapy, probiotic monotherapy, or TCM monotherapy in inducing clinical remission, reducing relapse rates, and lowering adverse events ( 6.3 Targeted delivery systems To address the limitations of oral administration, novel delivery platforms have been developed around three objectives: preserving probiotic viability and promoting colonization, achieving precise targeting of inflamed sites, and enabling synergistic, multipathway therapy
Luscher C, Xia H, Beattie EC, Carroll RC, von Zastrow M, Malenka RC et al (1999)
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approval had not been finalized as of mid-2026
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Fibronectin is a stress responsive gene regulated by HSF1 in response to geldanamycin
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