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Upon its efflux from cells, oxidised glutathione is exposed to the sequential action of enzymes located on the external face of the cell membrane: -glutamyl transpeptidase (GGT) generates glutamate 94 and the cysteinylglycine dipeptide, which is degraded by dipeptidases such as aminopeptidase N (APN), thereby releasing cysteine and glycine

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Cutting edge: nanogel-based delivery of an inhibitor of CaMK4 to CD4 + T cells suppresses experimental autoimmune encephalomyelitis and lupus-like disease in mice

A.AgustiniB.Khler-ForsbergO.CusinC.KatzD.SylviaL

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