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Granted, that statistic was affected by COVID-19, but chronic disease played a significant role as well

doi: 10.3390/ijms21176212

The hindgut microbiome contributes to host oxidative stress in postpartum dairy cows by affecting glutathione synthesis process

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found reduced oxidative stress in ASD children supplemented with Coenzyme Q10, and the supplementation also improved the childrens gastrointestinal problems and sleep disorders 35