10.1093/aje/kwn409 Hu B-J, Hu Y-N, Lin S, Ma W-J, Li X-R: Application of Lutein and Zeaxanthin in nonproliferative diabetic retinopathy
One preclinical study (Valdecantos et al., ADA 2024) showed combination benefit in obese rats
It directly neutralizes free radicals, but its role is even more sophisticated than that
doi: 10.1016/j.freeradbiomed.2018.05.074 38 BaiskhanovaDSchaferH
383 , 82103 (2019) Wang, K., Ren, H., Li, N., Tan, X., Dang, F.: Ratiometric fluorescence sensor based on cholesterol oxidase-functionalized mesoporous silica nanoparticle@ ZIF-8 core-shell nanocomposites for detection of cholesterol
Both have a place, but they are not interchangeable, and neither is a substitute for addressing an underlying medical cause when one exists