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In diet-induced obese (DIO) mouse models, NNMT inhibition led to approximately 35% reduction in white adipose tissue mass compared to controls

Without a modest calorie deficit, adequate protein, and regular movement, the fragment has far less to work with, because it influences how the body handles fat rather than forcing weight off on its own

At high doses, it could impact other nutrients such as folic acid

Requests to FDA for agency records should be sent to: Food and Drug Administration Division of Freedom of Information (HFI-35), 5630 Fishers Lane, Rockville, MD 20857

Future research is expected to shed more light into the potential benefits and uses of this NNMT inhibitor