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A separate cohort study from the Philippines demonstrated even more striking results: patients receiving 30 mL per day for 14 days achieved favorable outcomes in 87% of cases, compared to just 50% in the control group

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A subset of dedifferentiated -cells were at early stage to convert into -cell in LOsG-treated animals As a subset of FoxO1-deficient -cells adapts the -cell fate, resulting in hyperglucagonemia 22 , we determined pancreatic glucagon mRNA in LOsG-treated -cells, which were associated with low or absent FoxO1 expression

Faccini, Abbott, and Paulus 1990