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This preparation meets United States Pharmacopeia (USP) standards for non-pyrogenic sterility and is formulated with benzyl alcohol as the bacteriostatic preservative agent to permit repeated aseptic withdrawals from the vial without microbial contamination

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Proper diagnostic tests use serum B12, methylmalonic acid, and homocysteine levels to provide accurate diagnosis when standard tests fail

However, these preclinical findings do not establish safety for use during human pregnancy, as species differences in placental transfer and fetal metabolism may exist

And this is through a keratinocyte-linked pathway involving p53