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Approximately 6% of people under age 60 and 20% of people over age 60 are vitamin B12 deficient

40 LojoN.RasicZ.Zenko SeverA.KolencD.VukusicD.DrmicD.et al (2016)

Managing side effects during dose escalation Side effects are part of the tirzepatide experience for most users, particularly during dose escalation

Much of a B12 hydroxocobalamin injection is excreted in urine within 48 hours of the injection

Investigations should also be conducted if patients are undergoing surgical or endoscopic therapy for GERD

Patients not considered to have a high risk and those who opt not to receive medical therapy are offered colonoscopy 6 to 12 months after surgery