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Prior studies investigated the potential of CS NPs as oral medication delivery vehicles for renal disease 32

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doi: 10.1161/CIRCULATIONAHA.105.594077 175

While this effect appears to be related to the magnitude and rapidity of glucose lowering rather than a direct effect of the medication itself, patients with a history of diabetic retinopathy should undergo careful ophthalmologic evaluation before and during treatment, and the potential risks should be weighed against the expected benefits of improved glycemic control

probiotics/prebiotics integrate readily with lifestyle programs, suit prevention and maintenance, and are easier to standardize, albeit with modest and variable effect sizes [242,243,244,245,246,247, 256,257,258]

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