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doi: 10.3389/fphar.2014.00168 Received 11 May 2014 Accepted 25 June 2014 Published 17 July 2014 Volume 5 - 2014 Edited by Alfonso Pompella, Universit di Pisa, Italy Reviewed by Jose A

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For therapeutic uses of drugs that can cause hypersensitivity reactions, the risk of hypersensitivity development is often weighted against the therapeutic benefit of the drug, given that subsequent accidental or unintentional exposure to the same molecule would be unlikely

And again, separate from peptides, separate from compounds, you get into the whole world of biologics and the future of biologics and stem cells and creating a regulatory pathway

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-Glutamylcyclotransferase (GGCT) is a key enzyme catalyzing 5-oxoproline formation in the - glutamyl cycle