Chronic sleep deprivation (consistently less than 7 hours or poor-quality sleep) accelerates every hallmark of aging: increased inflammation, impaired glucose metabolism, reduced growth hormone production, accelerated cognitive decline, weakened immune function, and increased cortisol
Unsafe combinations include high-strength retinoids, certain prescription drugs, and injectable whitening cocktails that may overburden the liver
Pickart and Margolina's review provides the broader gene expression context for why these effects occur
Neutrophil extracellular traps persist at high levels in the lower respiratory tract of critically ill COVID-19 patients
NFkappaB modulators
doi:10.1002/nbm.2960 Ng F, Berk M, Dean O, Bush AI (2008) Oxidative stress in psychiatric disorders: evidence base and therapeutic implications