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Biomed Pharmacother 2003

The relationship between stress and cognitive decline is complex and involves various mechanisms which we have already explored, but another major factor is the prolonged release of stress hormones

With recent technology and ongoing advances in the scientific field, methods have been developed to synthesize complex peptide preparations from the extracts of several different tissues

Additional biochemical assays were used to test the ability of compounds to inhibit nicotinamide phosphoribosyl transferase (NAMPT) and NAD + -dependent protein deacetylase sirtuin 1 (SIRT1), two enzymes in the NAD + biosynthesis/salvage pathway

Hormone replacement therapy - current recommendations