Lpez-Burillo S, Tan DX, Mayo JC, Sainz RM, Manchester LC, Reiter RJ
When over-exposed to toxins (chemicals, hormone metabolites, alcohol, etc), the specialized cytochrome P450 enzymes in the liver are activated
J.BatistaA
Naturally, we are all unique, we will each react differently to IV therapy
Research models with obesity, insulin resistance, or age-related metabolic decline typically show both AMPK suppression (which MOTS-c corrects) and NNMT overexpression (which 5-Amino-1MQ corrects)
Low GSH in aging is associated with lower intake of GSH precursors, mainly cysteine, and lower GSH synthesis evidencing diminished function of nuclear factor erythroid 2related factor 2 (Nrf2)-dependent inductive mechanisms that enhance glutamate cysteine ligase expression, rate limiting factor for the synthesis of GSH (McCarty and DiNicolantonio, 2015)