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Concretely, lactylation of K477 on nucleolin (NCL), an RNA-binding protein in the nucleus, upregulates MAP kinase-activating death domain protein (MADD) through binding to its primary transcript and avoiding alternative splicing that generates premature termination in iCCA cells

Untersttzung der Wundheilung Die kupferbindende Eigenschaft macht GHK-Cu zu einem wichtigen Co-Faktor fr die Lysyloxidase ein Enzym, das Kollagen- und Elastinfasern stabil vernetzt

828 The GPX4-binding protein OTU deubiquitinase 5 (OTUD5) reduces the sensitivity of cells to ferroptosis by stabilizing GPX4

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This shift is much needed