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Plateau risk also depends on lifestyle factors outside medication

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doi: 10.3233/JAD-142265

For example, in ketotic dairy cows, the ruminal level of the tryptophan metabolite indole-3-acetic acid (IAA) is significantly reduced and is accompanied by downregulation of epithelial tight junction proteins, increased inflammatory mediators, and impaired barrier function

Human -Defensin-2 induction in nasal mucosa after administration of bacterial Lysates

De Smet et al., 2013)