The formula is: Daily sublingual dose = (Weekly injectable dose x Injectable bioavailability) / (7 days x Sublingual bioavailability) Using 80% injectable and 30% sublingual bioavailability as the midpoint estimate: Daily sublingual = (Weekly injectable x 0.80) / (7 x 0.30) = Weekly injectable x 0.38 This means a 10 mg weekly injectable dose translates to approximately 3.8 mg daily sublingual
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As people age, their ability to absorb B12 from food declines due to atrophic gastritis, which reduces stomach acid production
Selection of condensing agents: Commonly used condensing agents include DIC/HOBt, HBTU/HOBt, etc
In some embodiments, the viscosity modulating agent is petroleum jelly
If you experience increased pain or swelling at the injection site, prolonged numbness or tingling in your hand or fingers, severe allergic reactions such as difficulty breathing or swelling of the face or throat, or excessive bleeding that does not subside within a few minutes, it is crucial to seek medical attention immediately
