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A huge portion of the body's immune system resides in the gut, and chronic, low-grade systemic inflammation often originates from gut dysbiosis

in vivo not known at level of ER, but saturating levels of 25-40 mM use in vitro with unactivated microsomes and 2-10 mM with activation (e.g

During mastication they are enzimatically converted into thiocyanates, goitrin metabolites, that cause a competitive inhibition of the sodium/iodide symporter, thus inhibiting the thyroid hormones synthesis and possibly causing hypothyroidism [156]

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