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Animal studies show co-administration of BPC-157 with NSAIDs almost completely prevented gastric lesion formation

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Unresolved questions and future directions Currently, despite promising prospects in preclinical models, targeting glutamine metabolism faces challenges in clinical trials due to inherent heterogeneity in glutamine metabolism within tumor cells and immune cells, as well as its complex impact on immune responses

Acknowledgments We gratefully acknowledge Laboratori Farmaceutici Krymi (Rome, Italy) for their technical assistance and for kindly providing GSH-C4 and all clinical study medical devices as a gift

Cagrilintide is not yet available outside of clinical trials

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