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Most drugs are excreted by the kidney into the urine

PLoS ONE 7(3):e33258 Li W et al (2022) Mitochondria bridge HIF signaling and ferroptosis blockage in acute kidney injury

If desired, the removal of the GST affinity tag is accomplished by using a site-specific protease recognition sequence located between the GST moiety and the target protein

For clinical studies, sufficient preclinical testing should be performed using standardized extracts before they can be subjected to clinical studies

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