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However, some rare side effects of too much vitamin B12 can include: Headache Weakness Nausea Diarrhea Tingling sensations in the hands and feet Allergic reactions or skin rash (uncommon) When To Seek Medical Advice Risk of vitamin B12 deficiency: Groups at a higher risk of vitamin B12 deficiency include older adults, people who only eat plant-based foods (vegans and vegetarians), and those with certain chronic conditions (gastrointestinal disorders that can affect vitamin absorption)

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Elevated homocysteine levels in mothers with neural tube defects: a systematic review and meta-analysis

Cytoprotective Research In vitro studies have documented quantifiable changes in oxidative stress biomarkers and mitochondrial membrane potential parameters across cellular integrity research models

Rutin exhibits diverse pharmacological properties, including anticancer, anti-inflammatory, neuroprotective, and antioxidant effects [172, 173]