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Lower dose vitamin C (200 mg/day) had no effect

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Astaxanthin mitigates oxidative stress and neuronal death via the SIRT1/NRF2/Prx2/ASK1/p38 signaling pathway, enhances neurological function, and provides neuroprotection following traumatic brain injury [73]

This study was supported by the Guangdong Basic and Applied Basic Research Foundation (2024A1515011821), the Science and Technology Projects in Guangzhou (2025A03J4226), and the Longgang District Science and Technology Innovation Bureau Project (LGKCYLWS 2024-9)

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Fig 1: Vitiligo disease During the process of wound healing, reduced expression of the adhesion molecule E-cadherin is thought to promote the movement of melanocytes