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[11] Long-term metformin therapy reduces calcium-dependent intrinsic-factor binding, lowering B12 absorption and potentially necessitating higher or more frequent parenteral doses

One study reported that vitamin B12 deficiency was associated with twice the risk of severe depression (4)

Its selectivity is just as important

Researchers should evaluate the product based on batch documentation, identity verification, and proper laboratory handling rather than color alone

To make sure this medicine is safe for you, tell your doctor if you have: eye problems or Leber's disease (in you or a family member)

A knowledgeable provider ensures you are receiving a high-quality product at a clinically appropriate dose, which is fundamental for both safety and effectiveness