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Since the methionine cycle and the TSS pathway are closely connected with the former providing homocysteine for utilization in the latter, we determined the expression of the factors involved in the methionine cycle

3), which may contribute to the high level of GSH and high GSH/GSSG ratio in the HT+GSH treatment compared to the HT treatment

Statements Author contributions CL and GK participated in the design, writing, and final corrections of the manuscript

Changing global epidemiology of liver cancer from 2010 to 2019: NASH is the fastest growing cause of liver cancer

The function of GSH in hepatocytes has been investigated by pharmacological inhibition or genetic ablation of the glutamate-cysteine ligase (GCL), the rate-limiting and regulatory enzyme in GSH biosynthesis

About this article Cite this article Chaudhary, D., Agarwal, H., Mishra, A