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Memantine is a NMDAR inhibitor which has shown to improve hydration of RBCs of patients with SCD in vitro and to reduce sickling in the setting of deoxygenation

Direct evidence for the formation of a complex between 1-cysteine peroxiredoxin and glutathione S-transferase pi with activity changes in both enzymes

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[6] The longer half-life is called the terminal half-life and the half-life of the largest component is called the dominant half-life