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Nebulized Bicarbonate + N-acetylcysteine (NAC) 3mL 4.2% Bicarb (1.5 mL 8.4% diluted in 1.5mL Sterile Water) combine w/ 3mL NAC (for acidic inhalation, do not mix with other drugs or use if non-acidic inhalation) Albuterol + NAC Albuterol 2.5mg in 3mL combined with 3mL NAC (may repeat q 4-6 hrs) Corticosteroids Inhaled (can nebulize or use inhalant device) : Budesonide 0.5mg-2.0mg BID or Fluticasone 200mcg BID Administration via IV/IO: Dexamethasone 8mg IV/IO q6hrs or Solu-medrol 125mg IV/IM q6hrs Toxic Industrial Chemical/Toxic Industrial Material/Vesicant Eye Injury Treatment Protocol Tetracaine Eye Drops for Pain Severe Vesicant Inhalation Protocol Combine in a nebulizer q 4-6 hrs: (1) Albuterol bullet, 2.5mg in 3mL , (2) NAC 20%, 3mL (2) Lidocaine 4% or 2%, 1 mL Complications & Adverse Effects: Lidocaine can create an airway protection issue if casualty has altered level of consciousness
Padamsey, Z., Rochefort, N.L., 2023
52 Consequently, a novel regulation mode of lactylation using lactate as a direct donor without necessitating the formation of lactyl-CoA is proposed, expanding the substrate range of lactylation
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6 Image Credit: Bondar Illia / Shutterstock.com Practical guidance To maximize allicin formation, fresh garlic should be crushed, minced, or grated to allow alliinase activation before heating
