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Radiation-induced downregulation of BACH transcriptional regulator 1 (BACH1), a transcriptional repressor of SLC7A11 , further sensitizes cells to cuproptosis 170

Hence, the safety associated with copper delivery through the skin needs to be established

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Muller-Lissner SA, Kamm MA, et al

NACAs characteristics as a drug were improved over NAC by neutralizing the carboxylic group of NAC, which makes the NACA pass cellular membranes easily, says Ercal