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J Allergy Clin Immunol Pract 2019

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Another approach involves modifying Lactobacillus plantarum to produce native GLP-1, which was shown to improve metabolic parameters, reduce inflammation, and restore -cell function in HFD/STZ mouse models of T2DM ( Of particular note is the ability of GLP1R agonists to induce transdifferentiation of intestinal cells into insulin-secreting cells

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