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While focusing on just one enzyme out of the approximately 1300 different types of enzymes in each human cell may seem oddly arbitrary, this research is crucial in furthering the treatment of psychiatric disorders and the development of more specific antipsychotic drugs
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(2013) 2:e00772
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Risk factors that should prompt consideration of B12 deficiency include advancing age (reduced stomach acid production), strict vegan or vegetarian diets, pernicious anaemia, gastrointestinal surgery (particularly gastric bypass or ileal resection), long-term use of certain medications (metformin, proton pump inhibitors, H2-receptor antagonists), nitrous oxide exposure (including recreational use), and conditions affecting the gut such as Crohn's disease or coeliac disease
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