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Lpez-Daz D, Delgado-Notario JA, Cleric V, Diez E, Merchn MD, Velzquez MM

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Discovery: Old Liver Meets Young Blood Pickart's 1973 discovery began with a comparison of fibrinogen synthesis in human liver tissue

PloS One 13 (14), e0195488

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Phase II takes these highly reactive, dangerous intermediates and binds (conjugates) them to endogenous molecules to neutralize them