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Because desensitization is essential for cell survival, cells may employ multiple, complementary protective mechanisms alongside uncoupling to be utilized depending on receptor characteristics or the surrounding environment

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While each system detoxifies specific peroxides via GPx or Prx, they share substrates and can compensate for one another when impaired

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They also tell us that they are sick less often and gain muscles and lose weight faster

Initial loading protocols often use daily or every-other-day dosing for the first one to two weeks, followed by weekly, then monthly maintenance