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Recheck IGF-1 at week 8

10.3389/fphar.2018.01163 79 LuM.TangF.ZhangJ.LuanA.MeiM.XuC.et al (2015a)

Their therapeutic efficacy in LC is markedly subtype-dependent, a critical factor for clinical translation

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IGF-1 LR3 and Muscle Growth Sequence Peptide Long R3 Insulin-like Growth Factor-I (IGF1 LR3) is an 83-amino acid analog of IGF-I, effectively containing the complete IGF-1 sequence but substituting glutamic acid (Glu) with arginine (Arg) at position 3, along with a 13-amino acid extension

Certain gut bacteria also deconjugate taurine and glycine from bile acids, reducing available amino acids for Phase II