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Ganguly, P., & Alam, S

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The peptide counteracted picrotoxin (non-competitive GABA receptor Cl channel blocker), isoniazid (inhibitor of glutamic acid decarboxylase and GABA synthesis), and bicuculline (GABA-A antagonist), all through dose-dependent protective effects without producing behavioral changes when administered alone

6 Inhibiting IGF-1R with teprotumumab, a mAb, has been shown to reduce the characteristic eye bulging (proptosis) and other serious clinical manifestations in patients with TED