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In the same line, a later cross-sectional study found that risk for schizophrenia has a maternal inheritance bias [111]

doi: 10.1136/ard.62.2.168 134 MigitaKIlyassovaBKovzelEFNersesovAAbiruSMaedaYet al

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34 Additionally, data from the 2-week and 12-week treatment phases of the study demonstrated an increased mean corpuscular volume, decreased mean corpuscular hemoglobin concentration, increased antioxidant capacity, and decreased markers of inflammation, hypercoagulability, adhesion, and serum erythropoietin level, suggesting potential pleiotropic salutary effects of PK activation in SCD

4 Discussion UA is the end product of endogenous purine metabolism

8 This study also had several limitations, including a small sample size, short study duration, and absence of existing data on optimal dosing